We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.
Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.
Read More
Most Useful Reviews
7.5
Joint health improvement
20 people found this helpful
This product effectively maintains joint health. Previously, I had ordered from other companies, but the results diminished. I read the composition carefully and found this one met the ideal glucosamine and chondroitin ratio. After a month, my joints have stopped crackling, and I've noticed improvements in my skin's elasticity as well.
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9
Works remarkably!
9 people found this helpful
Super!!! My knees suffer from arthritis. I hesitated to order these tablets but now I can say that the product works brilliantly! I can walk up stairs again, which I couldn’t do before. I will certainly order more and recommend it to my friends!
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9
Knee pain relief
9 people found this helpful
Excellent! It helped my knee stop hurting and reduced joint crunching. I've ordered it multiple times and even for my parents. I'm very pleased!
We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.
Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 56 Reviews
7.5
All Reviews
Positive Reviews
Negative Reviews
7.5
Joint health improvement
20 people found this helpful
This product effectively maintains joint health. Previously, I had ordered from other companies, but the results diminished. I read the composition carefully and found this one met the ideal glucosamine and chondroitin ratio. After a month, my joints have stopped crackling, and I've noticed improvements in my skin's elasticity as well.
Read More
9
Works remarkably!
9 people found this helpful
Super!!! My knees suffer from arthritis. I hesitated to order these tablets but now I can say that the product works brilliantly! I can walk up stairs again, which I couldn’t do before. I will certainly order more and recommend it to my friends!
Read More
9
Knee pain relief
9 people found this helpful
Excellent! It helped my knee stop hurting and reduced joint crunching. I've ordered it multiple times and even for my parents. I'm very pleased!
Read More
7.5
Immediate joint response
8 people found this helpful
I prefer this supplement in liquid form by NOW Foods. The joint results were felt immediately, especially with my daughter's joint crunching. After using this, the noise decreased significantly and even improved her mood, addressing her medical issue effectively. It supports cartilage integrity, which is crucial for my interests in treating damages caused by metabolic disorders.
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10
Quick recovery
4 people found this helpful
My doctor prescribed chondroitin and glucosamine for my knee pain. After a month on this product, the pain stopped. I've been advised to continue for three months.
An autoimmune disorder occurs when the body's immune system mistakenly attacks its own healthy cells and tissues, believing them to be foreign invaders, such as bacteria or viruses. This reaction can lead to inflammation, tissue damage, and impaired function of the affected organs. There are over 80 known autoimmune diseases, including rheumatoid arthritis, lupus, multiple sclerosis, and type 1 diabetes, each with its own specific symptoms and treatment options. The exact cause of these disorders is still unclear, but a combination of genetic, environmental, and hormonal factors is believed to play a role in their development.
Diagnosis of autoimmune disorders often involves a combination of physical examinations, assessment of symptoms, blood tests, and imaging studies to evaluate organ involvement. Treatment typically focuses on managing symptoms and controlling the immune response using medications such as corticosteroids, immunosuppressants, and biologics. In addition to medication, lifestyle modifications, such as stress management and a balanced diet, can be beneficial in managing symptoms. If you suspect you have an autoimmune condition, it's important to consult a healthcare professional for proper evaluation and tailored treatment options.
Glucosamine Chondroitin formulas are dietary supplements commonly used to support joint health and alleviate symptoms associated with osteoarthritis. These formulas typically contain glucosamine, a naturally occurring compound in the body that contributes to the formation and repair of cartilage, and chondroitin sulfate, which helps cartilage retain water and maintain its elasticity. Together, these ingredients are believed to promote joint function, reduce pain, and improve overall mobility, particularly in individuals who experience wear and tear on their joints due to age, physical activity, or injury.
The efficacy of glucosamine and chondroitin supplements can vary from person to person, and while some users report significant relief from joint discomfort, scientific studies on their effectiveness have produced mixed results. It's essential to consult with a healthcare provider before adding these supplements to your routine, especially if you have existing health conditions or are taking other medications. Many brands also blend these ingredients with additional vitamins, minerals, or herbal extracts to enhance their joint-supporting benefits, making it crucial to read labels and choose formulas that fit your specific needs.
Based on user reviews, many individuals taking this supplement for autoimmune disorders and joint issues report seeing results after approximately a month of consistent use. For instance, one user noted that after a month, their knee pain ceased, which aligns with other reviewers who also mentioned improvements in joint health and pain reduction within that timeframe Read Review.
However, some users have experienced benefits as early as a week, indicating that initial improvements can vary greatly among individuals Read Review. It's worth noting that the effectiveness of the supplement can depend on various factors, including the severity of the autoimmune condition and individual body responses. Continuing the regimen for at least three months is often suggested to achieve optimal results Read Review.
This supplement appears to have some support in scientific research for autoimmune disorders, particularly related to neuropsychiatric conditions. A study analyzed data from patients with KCNA2 IgG autoantibodies, which are linked to various neuropsychiatric issues such as cognitive impairment and seizures. Interestingly, the study found that early immunotherapy led to significant improvement in some patients, particularly those diagnosed with autoimmune encephalitis [1]. This emphasizes the potential role of targeted therapies in managing specific autoimmune issues, though further research is necessary to fully understand the implications and effectiveness of such treatments in broader contexts.
However, the findings highlight the variability of autoimmunity in patients, indicating that more comprehensive studies are essential to explore the therapeutic approaches further. As current evidence is still emerging, it’s crucial for individuals considering supplementation for autoimmune disorders to consult with healthcare professionals and rely on established treatment protocols until more definitive data is available [1].
Based on user reviews, many individuals have reported significant improvements in their joint health and overall mobility after using this supplement. Notably, one user shared that their knee pain ceased and joint crackling diminished after just a month of consistent use Read Review. This sentiment is echoed by others, such as a reviewer who indicated that they could once again navigate stairs comfortably, a feat they hadn’t been able to achieve prior to beginning the supplement Read Review.
A frequent theme among reviews is that users experience relief from joint pain and discomfort, often within a short time frame of starting the regimen. For instance, individuals noted enhancements in their physical activity levels—one user even mentioned that their mother's previously required injections could be postponed due to the supplement's efficacy Read Review. However, it's crucial to acknowledge that individual results can vary, as reflected by a few reviewers who did not experience the anticipated benefits, indicating that not everyone may respond positively to the supplement Read Review.
Users have reported varying experiences when combining this supplement with other dietary aids for managing autoimmune disorders. Some reviewers noted positive outcomes when combining this supplement with other specific vitamins and minerals, highlighting that such combinations can enhance joint functionality and overall wellness Read Review. For instance, one user mentioned their return to weightlifting after consistent use of the supplement alongside a broader regimen, indicating a synergistic effect that improved their exercise routine despite having an autoimmune issue Read Review.
On the other hand, some users reported limited success with the supplement alone, suggesting that it may not be effective for everyone or in isolation Read Review. A few individuals found it necessary to seek alternative formulations as the combination with other supplements did not yield the expected joint relief, revealing the importance of personalized supplementation routines Read Review. Overall, the evidence points to a mixed bag of experiences, highlighting the need for individuals with autoimmune conditions to carefully tailor their supplement strategies for optimal results.
Based on user reviews, the optimal dosage for Glucosamine Chondroitin formulas varies, with some users finding success with two capsules daily, while others have benefited from a dosage of three to four times a day. For example, one user reported significant improvements with just two capsules daily, while another indicated they had to increase to four capsules without experiencing any noticeable benefits Read ReviewRead Review. Users with autoimmune disorders also seem to report a general trend towards increased joint functionality and reduced pain after consistent use over weeks or months Read Review.
Furthermore, many recommend patience and continuity in taking the supplement, as several users noted that benefits became more pronounced after a few weeks of regular intake Read Review. It’s worth noting that while some users report remarkable improvements in their joint health, others have found no effect despite high dosages, indicating that the response to supplementation can be highly individualistic Read Review. Therefore, it may be advisable for users to consult with a healthcare professional to tailor the dosage to their specific condition and response.
10
Quick recovery
4 people found this helpful
My doctor prescribed chondroitin and glucosamine for my knee pain. After a month on this product, the pain stopped. I've been advised to continue for three months.
6
Skeptical but effective
87 people found this helpful
I bought this a year ago on my trainer's advice, who suggested certain minerals and supplements. Initially, I noticed little difference, but after a week of taking it again, I saw notable improvements. My knee pain ceased after a month of regular use, and I now periodically take it. It genuinely helps with joint functionality.
7.5
Joint health improvement
20 people found this helpful
This product effectively maintains joint health. Previously, I had ordered from other companies, but the results diminished. I read the composition carefully and found this one met the ideal glucosamine and chondroitin ratio. After a month, my joints have stopped crackling, and I've noticed improvements in my skin's elasticity as well.
9
Works remarkably!
9 people found this helpful
Super!!! My knees suffer from arthritis. I hesitated to order these tablets but now I can say that the product works brilliantly! I can walk up stairs again, which I couldn’t do before. I will certainly order more and recommend it to my friends!
9
Effective for mum
1 people found this helpful
Working!!! My mother, who is 67, is happy after I ordered it for her. She has unhealthy knees and previously required expensive injections every six months. After her course of treatment, her joints have not bothered her yet! It's impressive since it was time for another injection. I will order her a larger jar because it’s definitely effective!
2
No improvement noted
8 people found this helpful
Unfortunately, this product does not improve my joint condition. I took the capsules three times daily for three months and even increased it to four, but I felt no improvement. In fact, there was slight deterioration, leading me to order glucosamine with chondroitin from another manufacturer.
9
Exercise restored
I have an autoimmune disorder and can now exercise with heavy weights again after taking this regularly.
0
Unsatisfactory results
4 people found this helpful
This product simply doesn’t work for me at all. Even with an increased dose, I see no effect. I will not reorder it again. It feels like money down the drain.
8.5
Effective capsules
1 people found this helpful
These capsules are excellent, demonstrating clear results. They alleviate both crunching and pain in the joints, enhancing ease of movement. Overall, they positively affect well-being. Just two capsules daily are sufficient, but it’s essential to take them continuously. We are ordering another package.
9
Feel better quickly
1 people found this helpful
Excellent quality! I've known this brand for a long time. The dietary supplement consistently improves my health after the course. Notable improvements begin after the second week of use. The capsules are easy to swallow, and the packaging is reliable. Most importantly, there’s a positive result following the treatment. I recommend it.
We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.
Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.